In this paper, the changes of microstructure, strength and plasticity of Ti6Al4V-DT (TC4-DT) alloy are studied by metallographic microscope and tensile tester under different solid solution, cooling rates and aging treatments. The results demonstrate that the main influencing factors of tensile strength and plasticity are solution temperature and cooling methods. Solid solution and aging treatment at 550 ℃ for 8 h in the α+β phase and the single β phase region can obtain the bimodal structure and the lamellar structure, respectively. When the solid solution temperature rises below the phase transition temperature, the amount of primary α phase obviously decreases, meanwhile, the strength and plasticity are better in the two-phase region. As the cooling rate decreases, the lamellar α phase becomes coarsened under the solution treatment above the phase transition temperature, and the tensile strength and yield strength gradually decrease. Moreover, the size of α phase increases as the aging temperature increases at the α+β phase region. Furthermore, the dispersion strengthening of α phase makes the strength of the alloy higher at the lower aging temperature. In general, the strength and plasticity of TC4-DT alloy can be well matched, the tensile strength can reach up to 1017MPa and the elongation is 22% under solid solution treatment at 950 ℃ for 1.5 h, aging treatment at 550 ℃ for 8 h and in the air-cooled state.