β γ-TiAl alloy owns excellent deformability at high temperature, so it exhibits great potential in different fields in future. Ti-45Al-9(V, Nb, Y) alloys with different x=V/Nb (x=1, 1.5, 2, 3.5) were prepared, and their cyclic oxidation behavior in static air at 800 oC was investigated. The results show that Ti-45Al-9(V, Nb,Y) alloy possesses high oxidation resistance when x=1, due to the strip-like, continuous and dense Al2O3 layer. However, the Al2O3 layer becomes thinner with increasing of x=V/Nb, resulting in poor oxidation resistance of Ti-45Al-9(V, Nb,Y) alloy