Zr-Ti film was deposited on the surface of NiTi shape memory alloy (SMA) by balanced magnetron DC sputtering. The results of SEM, XRD and XPS indicate that the Zr-Ti film has the T-type crystal band structure with a fine and dense fibre character. The film has a good combination with NiTi substrate and a small amount of bioinert ZrO2 and TiO2 ceramics phases is found in the film. Blood compatibility was evaluated by hemolysis test and platelet adhesion test. The hemolysis of Zr-Ti film is less than that of NiTi SMA. And the number of platelets on the sample surface is also less than that of Zr-Ti film, which indicates the blood compatibility of NiTi SMA could be improved by the Zr-Ti film. Finally the depositing mechanism of the Zr-Ti film by magnetron sputtering was discussed