The friction wear properties of TC4 alloy and P110 tubing steel were comparatively studied at different temperatures. The changing rules of the wear rate, frication coefficient and topography of wear mark with the temperature were analyzed and the wear mechanism was also discussed. The results show that the wear resistance of P110 tubing steel excels obviously that of TC4 alloy. The wear resistance of TC4 changes a little with temperature rising and the wear mark is furrow morphology. The wear mechanism of TC4 alloy is delamination abrasion, adhesive abrasion and fatigue abrasion at lower temperature and delamination abrasion, adhesive abrasion and oxidation abrasion at higher temperature. The wear resistance of P110 tubing steel is decreased with temperature rising. The wear mark of P110 tubing steel is wear pit morphology and the wear mechanism is delamination abrasion and abrasive grain abrasion at lower temperature, while the wear mark is furrow morphology and the wear mechanism is delamination abrasion, adhesive abrasion and oxidation abrasion at higher temperature.