Four complexes Nd(C2F5COO)3Tfpy, Nd(C3F7COO)3Tfpy, Nd(C2F5COO)2(C6F5COO)Tfpy, and Nd(C2F5COO)3Phen were synthesized to investigate the effects of different ligands on fluorescent properties of Nd3+. Their structures were characterized by UV absorption spectra, FT-IR spectra and 1H NMR spectra. On the basis of testing absorption spectra, photoluminescence spectra and emission decay curves of each solution of the complexes, Judd-Ofelt(JO) analysis was carried out for each fluorescent solution. Structure analysis indicates that all ligands have successfully coordinated with central rare earth ions. Relatively small Ω2 obtained through JO analysis demonstrates that the coordination bonds between Nd3+ and the vicinity ligand are ionic for four complexes. The benzene rings of ligands are favorable for improving the fluorescence quantum efficiency of Nd3+. Compared with Phen, Tfpy is an excellent neutral second ligand because it has more asymmetric chemical structure and less hydrogen atoms. The four Nd(III)complexes all have potential to become liquid laser material because of their large stimulated emission cross sections.