The vaporation dynamics of Fe element in uramium melting during vacuum induction melting bave been studied, the results of experiment and calculation showed that the evaporation rate of Fe was first order with respect to Fe content in the metal. The activation energy of evaporation of Fe form uranium melt was obtained to be 121kJ/mol, and the rate of Fe evaporation is simultaneously controlled by the diffusion through the liquid boundary layer and the evaporation reaction of Fe at the metal/gas interface, in which the mass transfer coefficient was estimated to be from 4.52′10_-4cm/s at 1673K to 1.01′10_-3cm/s at 1853K.