The concept of material genome engineering has attracted extensive attention from researchers in the field of materials at home and abroad. As an important part of material genome engineering, high-throughput material synthesis and characterization technology become the focus of research, and which can significantly improve the speed of materials research and development. In this work, the related concepts of material genome engineering are briefly introduced. A series of representative high-throughput synthesis and characterization techniques are introduced,and the research progresses in this field are reviewed. The main developing trend of high-throughput material synthesis and characterization technology is discussed in order to provide new ideas for the development of this field, as well as providing references for further development of material genome engineering technology.