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氟转化处理AZ31B镁合金冠脉支架的血液相容性
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1.昆明理工大学 材料科学与工程学院,云南 昆明 650093;2.中国科学院金属研究所,辽宁 沈阳 110016

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Undergraduate Training Programs for Innovation and Entrepreneurship (201910674006)


Hemocompatibility of Fluoride Treated AZ31B Magnesium Alloys Used for Intravascular Stents
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Affiliation:

1.Faculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China;2.Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China

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Undergraduate Training Programs for Innovation and Entrepreneurship (201910674006)

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    摘要:

    基于镁及镁合金优异的生物降解性、生物相容性和综合力学性能,对镁合金在血管支架领域的应用进行了探索。采用转化处理在AZ31B镁合金表面成功制备出氟转化涂层;随后分别采用溶血实验、凝血试验和血小板黏附试验研究了氟转化处理后的AZ31B镁合金的血液相容性能;为了分析其血液相容性能的机制,同时开展了材料表面能的测定。结果表明,氟转化处理AZ31B镁合金在冠脉介入治疗领域极具应用潜力。

    Abstract:

    Due to the excellent biodegradability, biocompatibility and mechanical properties of magnesium alloy, the possibility of magnesium alloy as intravascular stent was studied. Firstly, based on our previous work, a compact fluoride conversion coating was prepared on the surface of AZ31B magnesium alloy. The hemolytic tests, blood coagulation tests and platelet adhesion tests were carried out to evaluate the hemocompatibility of the fluoride treated AZ31B magnesium alloy. The surface energy was measured to analyze the mechanism of the hemocompatibility of the samples. Results show that the fluoride treated AZ31B magnesium alloy has potential application value in intravascular stenting.

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颜廷亭,栗可心,蒋志敏,苗忻怡,李潘,陈庆华,谭丽丽,杨柯.氟转化处理AZ31B镁合金冠脉支架的血液相容性[J].稀有金属材料与工程,2022,51(2):469~473.[Yan Tingting, Li Kexin, Jiang Zhimin, Miao Xinyi, Li Pan, Chen Qinghua, Tan Lili, Yang Ke. Hemocompatibility of Fluoride Treated AZ31B Magnesium Alloys Used for Intravascular Stents[J]. Rare Metal Materials and Engineering,2022,51(2):469~473.]
DOI:10.12442/j. issn.1002-185X.20200932

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历史
  • 收稿日期:2020-12-03
  • 最后修改日期:2021-01-06
  • 录用日期:2021-02-04
  • 在线发布日期: 2022-03-03
  • 出版日期: 2022-02-28