To design a porous titanium alloy structure suitable for cervical implants, according to the different stress conditions of cervical vertebrae, such as compression, compression-shear, compression-torsion, compression-bending, four types of unit cell structures TO-C, TO-CS, TO-CT and TO-CB were constructed by combining topology optimization and CAD. The mechanical properties were analyzed by compression simulation. Finally, the quasi-static compression test of 60 % porosity porous specimens prepared by laser powder bed melting technology was carried out. The results of finite element simulation and compression test show that the compressive properties and elastic modulus of the four porous structures meet the requirements of human bone implants. Among them, the TO-CB structure has the best compressive performance and is suitable for porous titanium alloy cervical spine implants.