High-Entropy Alloys, a novel class of materials characterized by the statistical distribution of multiple principal elements on simple crystalline lattices, have emerged as a research hotspot in materials science and condensed matter physics due to their exceptional mechanical properties and unique high-entropy effects. Since the discovery of the first high-entropy superconductor in 2014, exploring their superconducting performance and advantages has progressively become a frontier in scientific research. The Ta-Nb-Hf-Zr-Ti system, in particular, exhibits remarkable mechanical robustness, outstanding radiation tolerance, and superconducting performance comparable to that of the binary NbTi alloy, positioning it as a promising candidate for advanced applications such asShigh-field superconducting magnets,Ssuperconducting electric motors, andSnext-generation nuclear fusion reactors. This review systematically summarizes global research progress on Ta-Nb-Hf-Zr-Ti-based superconductors, aiming to provide a comprehensive reference for advancing this burgeoning field.