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La2O3纳米纤维的制备及抗菌性能研究
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1.新型陶瓷与精细工艺国家重点实验室;2.中国人民解放军总医院医院

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国家自然科学基金资助(项目号51323001)


Synthesize and antibacterial performance of La2O3 nanofiber
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1.State Key Lab of Advance Ceramics Fine Processing,Tsinghua University;2.Center for Clinicla Laboratory Medicine,PLA General Hospital

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    摘要:

    本文采用电纺丝法制备了氧化镧纳米纤维,并通过X射线衍射(XRD),X射线光电子能谱(XPS),扫描电子显微镜(SEM),透射电子显微镜(TEM)以及比表面积分析(BET)分析了物相结构和显微形貌。探究了氧化镧纳米纤维的抗菌性能和机理。结果表明,静电纺丝法可成功制得高长径比,直径均匀且连续的氧化镧纳米纤维。该纤维在负载量极低(200 mg/L)的情况下,对高浓度革兰氏阴性大肠杆菌(107 CFU/L)具有超快速灭菌效果,可在100分钟内达到95%以上的细菌灭活率。通过长时间的培养和观察表明,该纤维具有彻底且长效的抑菌效果,长时间培养后未观察到细菌的反复增殖。此外,氧化镧纳米纤维对鲍曼不动杆菌和绿脓杆菌也具有良好的灭菌效果,是一种潜在的广谱抗菌材料。

    Abstract:

    La2O3 nanofibers was synthesized through electrospinning and heat treatment process. The phase structure, morphology and antibacterial performance were characterized by SEM, TEM, XRD, XPS and BET. The result shows that La2O3 nanofibers possessed high length–diameter ratio, uniform morphology and pure phase. The La2O3 nanofibers have an excellent germicidal effect against the high-risk human pathogen Escherichia coli O157. More than 95% inactivation rate of hige concentration bacterial (107 CFU/L) is achieved in 100 minutes by low addition of La2O3 nanofibers (200 mg/L) and no E. coil recovery was detected in following three days. Furthermore, La2O3 nanofibers shows high efficient bactericidal performance against Acinetobacter baumannii and P.aeruginosa, demonstrating its potential application as efficient and broad-spectrum antimicrobial material.

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邢岩,叶丽艳,成婧,潘伟. La2O3纳米纤维的制备及抗菌性能研究[J].稀有金属材料与工程,2020,49(2):676~681.[Yan Xing, Liyan Ye, Jing Cheng, Pan Wei. Synthesize and antibacterial performance of La2O3 nanofiber[J]. Rare Metal Materials and Engineering,2020,49(2):676~681.]
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  • 收稿日期:2019-04-20
  • 最后修改日期:2019-05-08
  • 录用日期:2019-10-23
  • 在线发布日期: 2020-03-12
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