Through a modified inherent strain model based on the minimum residual stress and deformation, three building schemes with different building postures and support structures were evaluated by finite element analysis. Results demonstrate that according to the principle of reducing the overall height of the building and reducing the support structure with a large tilt angle from the building direction, the residual stress and deformation can be effectively reduced by proper design of building posture and support before laser powder bed melting. Moreover, without the data of thermophysical property variation of Ti-6Al-4V artificial knee implants with temperature, predicting the residual stress and deformation with acceptable accuracy and reduced time cost can be achieved by the inherent strain model.