The effect of rapid quenching on phase structure and hydrogen storage performance of Ti-28V-15Mn-10Cr alloy is investigated. X-ray diffraction (XRD) results show that two phases of BCC and C14 Laves of the as-cast alloy are transformed into a single BCC phase after rapid quenching treatment. The lattice parameters of the alloy increase with increasing of quenching rate. It results in a flatter hydrogen absorption-desorption plateau and a lower hydrogen absorption-desorption plateau pressure. With increasing quenching rate,the activation of Ti-28V-15Mn-10Cr alloy becomes worse.